Senior Manager, Corporate Systems Administrator

Overview

Celldex is pioneering new horizons in immunology to deliver life-changing therapies. We are relentless in our pursuit of novel antibody-based treatments that engage the human immune system and directly affect critical pathways to improve the lives of patients with allergic, inflammatory and autoimmune disorders.

We have built a culture where innovative and talented people thrive-focusing a significant effort on attracting and retaining passionate and motivated employees who want to play a role in helping people with serious health conditions and who see this effort as personally rewarding. In our highly entrepreneurial environment, employees are empowered and the opportunity for professional development occurs every day.

Ready to make an impact? Learn more about joining the Celldex Team today!

The role ensures systems are reliable, compliant, and aligned with business objectives within a regulated life sciences environment.

The Sr. Manager, Corporate Systems Administrator is responsible for the administration, support, and continuous improvement of enterprise and corporate IT systems that enable business operations across G&A, Finance, Manufacturing and Supply Chain functions. This role partners with key business stakeholders to lead requirements definition and perform system enhancements and upgrades.

The position plays a critical role in ensuring system efficiency, data integrity, and compliance to financial controls.

Responsibilities

Corporate Systems Administration & Support

• Administer, configure, and support enterprise systems including ERP, finance, HR, procurement, and related applications.
• Manage user access, security roles, configurations, and system settings.
• Serve as escalation point for corporate application issues.

Business Partnership & Requirements Support

• Partner with Finance, HR, Manufacturing & Supply Chain stakeholders to understand system needs.
• Gather and translate business requirements into system configurations and enhancements.
• Support user training, adoption, and documentation.
• Lead cross‑functional ERP and enterprise system initiatives to streamline operations, improve workflows, and enhance system performance across clinical, commercial, and operational functions
• Elicit, analyze, and document business and functional requirements using BRDs, FRDs, user stories, acceptance criteria, and traceability matrices
• Translate complex business needs (pricing, sales performance, contracting, clinical and regulatory reporting) into functional specifications and scalable system designs
• Partner with stakeholders to troubleshoot and resolve issues across ERP, Supply Chain, Manufacturing and HR Systems as appropriate.
• SOX, GxP, Compliance & Validation
• SOX & IT General Controls Ownership: Own and administer SOX IT General Controls for ERP systems supporting financial reporting, including access management, segregation of duties, change management, and audit logging
• Audit & Compliance Support: Serve as the ERP subject‑matter expert for internal and external SOX audits by supporting walkthroughs, providing audit evidence, addressing auditor inquiries, and remediating control deficiencies in partnership with Finance and Internal Audit.
• ERP Security & Change Governance: Ensure ERP configurations, enhancements, and upgrades are securely implemented, properly authorized, tested, documented, and maintained to preserve financial data integrity and audit readiness.

Vendor & Change Management

• Coordinate with vendors and consultants for support and enhancements.
• Support system upgrades and process improvements.

Qualifications

• Bachelor''s Degree or equivalent experience
• 10+ years supporting enterprise or corporate systems.
• Experience supporting life sciences or regulated (GxP) environments.
• Excellent interpersonal skills and ability to communicate clearly, effectively, and professionally.
• Strong analytical skills with demonstrated ability to solve complex problems, resolve issues, and make practical recommendations and plans.
• Takes ownership of end-user issues and is proactive when interacting with end users to resolve issues
• Strong experience supporting ERP, Supply Chain, Manufacturing and HR systems
• Demonstrated expertise in business analysis, requirements management, and system design
• Working knowledge of SOX and FDA regulations, GxP, validation, and audit processes
• Experience with data analytics and reporting tools (e.g., Power BI, SQL)
• Proven ability to work cross‑functionally with technical and non‑technical stakeholders

Compensation

The expected base salary range for this position is $179,903 to $198,132.We are committed to compensating employees equitably based on several factors including experience, education, licensure/certifications, skill level, location of the position, and availability of similar talent in a competitive market.

Compensation for this role includes base salary, annual discretionary bonus, long term incentive, 401(K) plan with employer contribution, health care and other insurance benefits (for employee and family), paid holidays, vacation, and sick days.

A summary of our benefits can be found on our careers page.Celldex is proud to be an equal opportunity employer that strives to foster a culture of diversity, equity, and inclusion. We are committed to promoting a diverse environment through development, recruiting and community outreach

Skills

Analysis Skills, Antibodies, Auditing, Autoimmune Disease, Biology, Business Analysis, Business Operations, Change Management, Clinical Practices/Protocols, Communication Skills, Continuous Improvement, Customer Acquisition, Customer Relations, Data Analysis, Data Quality, Database Report Tools, Documentation, ERP (Enterprise Resource Planning), Entrepreneurship, Environmental Sciences, External Audit, FDA Requirements, Finance, Financial Audit, Financial Compliance, Financial Control, Financial Reporting, Functional Requirements Document (FRD), GxP, HRIS/HRMS, Identify Issues, Immunology, Inflammatory Diseases, Information Systems/Technology IS/IT Administration, Information Technology & Information Systems, Internal Audit, Interpersonal Skills, Manufacturing, Manufacturing Systems, Needs Assessment, Operational Improvement, Power BI, Pricing, Problem Solving Skills, Process Improvement, Procurement Software, Regulatory Reports, Requirements Management, Resolve Customer Issues, SQL (Structured Query Language), Sales, Sarbanes-Oxley Act (SOX), Staff Motivation, Supply Chain, Systems Administration/Management, Systems Scalability, Traceability

About the Company

Celldex Therapeutics Inc